The glial scar that blocks regrowth
Completeness of injury is the single biggest predictor. Patients with preserved partial function (incomplete injury) have markedly better recovery prospects than those with a complete lesion, and that should be explained before any decision.
Delivery routes and their risks
Delivery routes differ — intravenous, intrathecal, or direct injection at the lesion during surgery — and each carries its own risk. Local injection in particular is invasive and belongs only in centres with a neurosurgical team.
Rehabilitation that actually works
What is proven to help is intensive rehabilitation, pressure-sore prevention, bladder and bowel management and neuropathic pain control. Families should invest there first, then consider adjunct options with full information.