How high glucose damages nerves
Symptoms usually start at the toes and creep upward, and many patients present only after sensation is already lost. That is dangerous: a foot wound stops hurting and can progress fast, which makes an annual foot exam as important as any treatment.
Rebuilding the microvasculature
In studies, MSCs are used to stimulate angiogenesis and reduce inflammatory mediators around nerves. Reported outcomes tend to be improvements in pain scores and walking distance rather than full return of sensation.
A sensible care plan
A sensible plan is hitting the HbA1c target, stopping smoking, daily foot care and prescribed neuropathic pain medication — and if cell therapy is considered, doing it under medical assessment with standardised before-and-after measurement.