Numbness, burning pain and blood flow at the feet
Quick answer
Diabetic peripheral neuropathy comes from chronic high glucose damaging both nerves and the microvessels that feed them. The cell therapy rationale is to promote new capillaries and reduce inflammation, which may ease numbness and burning in some patients — but glucose control remains the decisive factor.
Symptoms usually start at the toes and creep upward, and many patients present only after sensation is already lost. That is dangerous: a foot wound stops hurting and can progress fast, which makes an annual foot exam as important as any treatment.
In studies, MSCs are used to stimulate angiogenesis and reduce inflammatory mediators around nerves. Reported outcomes tend to be improvements in pain scores and walking distance rather than full return of sensation.
A sensible plan is hitting the HbA1c target, stopping smoking, daily foot care and prescribed neuropathic pain medication — and if cell therapy is considered, doing it under medical assessment with standardised before-and-after measurement.
Partly, if nerves are not permanently damaged; established damage rarely reverses completely.
There is no standard number; a physician sets it based on severity and response.
Diabetic peripheral neuropathy comes from chronic high glucose damaging both nerves and the microvessels that feed them. The cell therapy rationale is to promote new capillaries and reduce inflammation, which may ease numbness and burning in some patients — but glucose control remains the decisive factor.
Root cause: Chronic hyperglycaemia
5 points • reviewed 2026-08-28
Reviewed and last updated: 2026-08-28
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Last updated: 2026-08-28 · This content is for information only and is not medical advice. Consult a qualified doctor before making treatment decisions.
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