Skip to content
Cover: a clear conditioned-media serum vial on white

EHL-Stem conditioned media: the real data on brightening and wrinkles

An INCI-registered cosmetic ingredient from EHL Bio

Quick answer

Stem cell conditioned media is the fluid produced while culturing stem cells, containing growth factors, cytokines, fibronectin and collagen. EHL Bio's EHL-Stem is INCI-registered as Human Adipose Stromal Cell Conditioned Media. Independent laboratory testing (Dermapro, January 2016) reported a 49% reduction in melanin production, 45% inhibition of tyrosinase and roughly a 9-fold increase in intracellular collagen synthesis.

Key facts

INCI name
Human Adipose Stromal Cell Conditioned Media
Application no.
5-09-2014-2745
Melanin reduction
49% (in vitro, Dermapro 2016)
Collagen increase
3.69 → 33.32 mg/g (~9x)
Key growth factors
VEGF, FGF, TGF, PDGF, HGF, EGF

What in-vitro numbers really mean

Those figures come from cell-level (in vitro) assays, not randomised controlled human application trials, so read them as ingredient potential rather than a promise that every finished product containing it performs identically.

Growth factors identified in EHL-Stem

Analysed components in EHL-Stem include VEGF, FGF, TGF, PDGF, HGF and EGF — growth factors tied to angiogenesis, tissue repair and fibroblast stimulation.

Safety criteria for conditioned media

On safety, the company states it uses only conditioned media meeting Korea's MFDS safety criteria, with safety studies run with GLP-accredited Biotoxtech, and formulations free of parabens, alcohol and colourants.

The bottom line for Thai consumers

Bottom line for Thai consumers: conditioned media is a topical cosmetic ingredient, not a disease treatment. If you see claims that injected conditioned media treats disease, check its legal status carefully.

Frequently asked questions

  • Does conditioned media contain cells?

    No. Cells are filtered out, leaving only the factors they secreted.

  • How long until visible results?

    Hydration can improve quickly, but wrinkle and brightness changes usually need 8-12 weeks of consistent use, in line with skin turnover.

  • Is it suitable for sensitive skin?

    Paraben-, alcohol- and fragrance-free formulas are usually low irritation, but patch-test on the inner arm for 48 hours before facial use.

  • How does it differ from ordinary growth factor serums?

    Source. Conditioned media is a natural multi-factor mixture from actual culture, whereas some serums add just one recombinant growth factor.

Share this page

Last updated: 2026-08-28 · This content is for information only and is not medical advice. Consult a qualified doctor before making treatment decisions.

Back to categories

Skin & laser before & after cases

Banobagi

View full gallery

    Related topics: Cell technology

    See all in this category